By Ilene S. Ruhoy, MD, PhD As we get older, even if we are healthy, all organs undergo change with each passing decade. And our brains are no exception. Age-related changes of the brain are not necessarily indicative of disease or degeneration. Brain cells no longer divide after we are born as do many other […]
The latest research in anti-aging and regenerative medicine has been focused on senescent cells and the role they play in the aging process, the body’s ability to heal, and chronic inflammatory disease. A senescent cell is one that undergoes changes in gene expression resulting in a loss of the ability to replicate, apoptosis or programmed […]
What is happening in a traumatic brain injury or concussion? The brain has about 10 billion capillaries in a highly specialized endothelial lining flush with tight junctions, basement membranes, pericytes & astrocyte projections. This blood-brain barrier (BBB) admits molecules sized at 400 daltons and less (as a comparison, alcohol is 200 daltons per molecule which […]
The connection between our guts and our brains cannot be denied. While the relationship between the gut and the brain has been known since the 19th century in terms of control of peristalsis, or motility, we have developed a greater understanding of just how important the crosstalk is between the two organs. The burgeoning field […]
TEN Ways To Stimulate Autophagy What is autophagy and why do we need it? Autophagy is the cellular process by which the cells are cleaned out. The organelles, proteins, and debris, that are no longer efficient nor effective, are packaged and sent on their way either by degradation or release. Autophagy can dictate not only […]
The Importance of Oxygen in Healing and Pain Oxygen is the most essential molecule needed for life. We can live for weeks without food, days without water, but only moments without oxygen. Our body’s tissues need a constant supply of oxygen to function and the best way to optimize health is to adequately oxygenate the […]
Can We Make New Brain Cells As An Adult? The human brain is known to develop from conception until about the age of 21 years. During childhood, it goes through critical growth spurts and new neurons develop at a rapid pace. From our teenage years through our young adult years the most important region of […]
Detoxification seems to be a buzz word these days. It is certainly a key phrase that gets people’s attention. But what is detoxification? What does it mean to detoxify? And how is our brain involved? Physiologically, detoxification is an essential cellular function that without the means to do so would be incompatible with life, at […]
A little starvation can really do more for the average sick man than can the best medicine and the best doctors – Mark Twain Intermittent or time restricting eating simply means periods of eating and periods of not eating. Fasting has been a natural part of human history for thousands of years and current research […]
Mast cells are implicated in a wide array of disorders. At one extreme is mastocytosis with a true proliferation of mast cells. At the other end, and often all in between, are the mast cell activation disorders where there is episodic activation and degranulation of mast cells and release of their contents, mainly histamine, causing […]
